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Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation – A Report from CIBMTR

Identifieur interne : 003810 ( Main/Exploration ); précédent : 003809; suivant : 003811

Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation – A Report from CIBMTR

Auteurs : Sally Arai [États-Unis] ; Mukta Arora [États-Unis] ; Tao Wang [États-Unis] ; Stephen R. Spellman [États-Unis] ; Wensheng He [États-Unis] ; Daniel R. Couriel [États-Unis] ; Alvaro Urbano-Ispizua [Espagne] ; Corey S. Cutler [États-Unis] ; Andrea A. Bacigalupo [Italie] ; Minoo Battiwalla [États-Unis] ; Mary E. Flowers [États-Unis] ; Mark B. Juckett [États-Unis] ; Stephanie J. Lee [États-Unis] ; Alison W. Loren [États-Unis] ; Thomas R. Klumpp [États-Unis] ; Susan E. Prockup [États-Unis] ; Olle T. H. Ringdén [Suède] ; Bipin N. Savani [États-Unis] ; Gérard Socié [France] ; Kirk R. Schultz [Canada] ; Thomas Spitzer [États-Unis] ; Takanori Teshima [Japon] ; Christopher N. Bredeson [Canada] ; David A. Jacobsohn [États-Unis] ; Robert J. Hayashi [États-Unis] ; William R. Drobyski [États-Unis] ; Haydar A. Frangoul [États-Unis] ; Görgün Akpek [États-Unis] ; Vincent T. Ho [États-Unis] ; Victor A. Lewis [Canada] ; Robert Peter Gale ; John Koreth [États-Unis] ; Nelson J. Chao [États-Unis] ; Mahmoud D. Aljurf [Arabie saoudite] ; Brenda W. Cooper [États-Unis] ; Mary J. Laughlin [États-Unis] ; Jack W. Hsu [États-Unis] ; Peiman Hematti [États-Unis] ; Leo F. Verdonck [Pays-Bas] ; Melhelm M. Solh [États-Unis] ; Maxim Norkin [États-Unis] ; Vijay Reddy [États-Unis] ; Rodrigo Martino [Espagne] ; Shahinaz Gadalla [États-Unis] ; Jenna D. Goldberg [États-Unis] ; Philip L. Mccarthy [États-Unis] ; José A. Pérez-Sim N [Espagne] ; Nandita Khera [États-Unis] ; Ian D. Lewis [Australie] ; Yoshiko Atsuta [Japon] ; Richard F. Olsson [Suède] ; Wael Saber [États-Unis] ; Edmund K. Waller [États-Unis] ; Didier Blaise [France] ; Joseph A. Pidala [États-Unis] ; Paul J. Martin [États-Unis] ; Prakash Satwani [États-Unis] ; Martin Bornh User [Allemagne] ; Yoshihiro Inamoto [États-Unis] ; Daniel J. Weisdorf [États-Unis] ; Mary M. Horowitz [États-Unis] ; Steven Z. Pavletic [États-Unis]

Source :

RBID : PMC:4326247

Descripteurs français

English descriptors

Abstract

Although transplant practices have changed over the last decades there is no information on trends in incidence and outcome of cGVHD over time. This study utilized the central database of the Center for International Blood and Marrow Transplant Research (CIBMTR) to describe the time trends for cGVHD incidence, non-relapse mortality, and the risk factors for cGVHD. The 12-year period was divided into three intervals: 1995-1999, 2000-2003, 2004-2007, and included 26,563 patients with acute leukemia, chronic myeloid leukemia and myelodysplastic syndrome. In the multivariate analysis, the incidence of cGVHD was shown to be increased in more recent years (odds ratio= 1.19, p<0.0001) and this trend was still seen when adjusting for donor type, graft type, or conditioning intensity. In patients with cGVHD, non-relapse mortality has decreased over time, but at 5-years there were no significant differences among different time periods. Risk factors for cGVHD were in line with previous studies. This is the first comprehensive characterization of the trends in cGVHD incidence and underscores the mounting need for addressing this major late complication of transplantation in future research.


Url:
DOI: 10.1016/j.bbmt.2014.10.021
PubMed: 25445023
PubMed Central: 4326247


Affiliations:


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Le document en format XML

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<name sortKey="Flowers, Mary E" sort="Flowers, Mary E" uniqKey="Flowers M" first="Mary E." last="Flowers">Mary E. Flowers</name>
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<name sortKey="Lee, Stephanie J" sort="Lee, Stephanie J" uniqKey="Lee S" first="Stephanie J." last="Lee">Stephanie J. Lee</name>
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<region type="state">Washington (État)</region>
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<wicri:cityArea>Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle</wicri:cityArea>
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<name sortKey="Loren, Alison W" sort="Loren, Alison W" uniqKey="Loren A" first="Alison W." last="Loren">Alison W. Loren</name>
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<region type="state">Pennsylvanie</region>
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<name sortKey="Klumpp, Thomas R" sort="Klumpp, Thomas R" uniqKey="Klumpp T" first="Thomas R." last="Klumpp">Thomas R. Klumpp</name>
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<name sortKey="Prockup, Susan E" sort="Prockup, Susan E" uniqKey="Prockup S" first="Susan E." last="Prockup">Susan E. Prockup</name>
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<region type="state">État de New York</region>
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<name sortKey="Ringden, Olle T H" sort="Ringden, Olle T H" uniqKey="Ringden O" first="Olle T. H." last="Ringdén">Olle T. H. Ringdén</name>
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<region type="state">Tennessee</region>
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<name sortKey="Socie, Gerard" sort="Socie, Gerard" uniqKey="Socie G" first="Gérard" last="Socié">Gérard Socié</name>
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<wicri:regionArea>Division of Hematology, Hopital Saint Louis, Paris</wicri:regionArea>
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<region type="region">Île-de-France</region>
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<name sortKey="Schultz, Kirk R" sort="Schultz, Kirk R" uniqKey="Schultz K" first="Kirk R." last="Schultz">Kirk R. Schultz</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Pediatric Hematology/Oncology/BMT, British Columbia’s Children’s Hospital, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
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<name sortKey="Spitzer, Thomas" sort="Spitzer, Thomas" uniqKey="Spitzer T" first="Thomas" last="Spitzer">Thomas Spitzer</name>
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<country xml:lang="fr">États-Unis</country>
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<region type="state">Massachusetts</region>
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<wicri:cityArea>Department of Bone Marrow Transplant-Oncology, Massachusetts General Hospital, Boston</wicri:cityArea>
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<name sortKey="Teshima, Takanori" sort="Teshima, Takanori" uniqKey="Teshima T" first="Takanori" last="Teshima">Takanori Teshima</name>
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<nlm:aff id="A22">Kyushu University Hospital, Fukuoka, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Kyushu University Hospital, Fukuoka</wicri:regionArea>
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<name sortKey="Bredeson, Christopher N" sort="Bredeson, Christopher N" uniqKey="Bredeson C" first="Christopher N." last="Bredeson">Christopher N. Bredeson</name>
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<nlm:aff id="A23">Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada</nlm:aff>
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<wicri:regionArea>Department of Medicine, The Ottawa Hospital, Ottawa, ON</wicri:regionArea>
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<name sortKey="Jacobsohn, David A" sort="Jacobsohn, David A" uniqKey="Jacobsohn D" first="David A." last="Jacobsohn">David A. Jacobsohn</name>
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<nlm:aff id="A24">Division of Blood and Marrow Transplantation Center for Cancer and Blood Disorders, Children’s National Health Systems, Washington, DC</nlm:aff>
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<region type="state">District de Columbia</region>
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<name sortKey="Hayashi, Robert J" sort="Hayashi, Robert J" uniqKey="Hayashi R" first="Robert J." last="Hayashi">Robert J. Hayashi</name>
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<nlm:aff id="A25">Division of Pediatric Hematology/Oncology, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO</nlm:aff>
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<placeName>
<region type="state">Missouri (État)</region>
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<name sortKey="Drobyski, William R" sort="Drobyski, William R" uniqKey="Drobyski W" first="William R." last="Drobyski">William R. Drobyski</name>
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<nlm:aff id="A26">Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
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<placeName>
<region type="state">Wisconsin</region>
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<author>
<name sortKey="Frangoul, Haydar A" sort="Frangoul, Haydar A" uniqKey="Frangoul H" first="Haydar A." last="Frangoul">Haydar A. Frangoul</name>
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<nlm:aff id="A27">Division of Hematology-Oncology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Tennessee</region>
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<wicri:cityArea>Division of Hematology-Oncology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
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<name sortKey="Akpek, Gorgun" sort="Akpek, Gorgun" uniqKey="Akpek G" first="Görgün" last="Akpek">Görgün Akpek</name>
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<nlm:aff id="A28">Section of Hematology Oncology, Banner MD Anderson Cancer Center, Gilbert, AZ</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<region type="state">Arizona</region>
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<name sortKey="Ho, Vincent T" sort="Ho, Vincent T" uniqKey="Ho V" first="Vincent T." last="Ho">Vincent T. Ho</name>
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<nlm:aff id="A8">Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff>
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<region type="state">Massachusetts</region>
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<name sortKey="Lewis, Victor A" sort="Lewis, Victor A" uniqKey="Lewis V" first="Victor A." last="Lewis">Victor A. Lewis</name>
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<nlm:aff id="A29">Departments of Oncology, Paediatrics, Alberta Children’s Hospital, Calgary, AB, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
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<name sortKey="Gale, Robert Peter" sort="Gale, Robert Peter" uniqKey="Gale R" first="Robert Peter" last="Gale">Robert Peter Gale</name>
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<author>
<name sortKey="Koreth, John" sort="Koreth, John" uniqKey="Koreth J" first="John" last="Koreth">John Koreth</name>
<affiliation wicri:level="2">
<nlm:aff id="A8">Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea>
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</author>
<author>
<name sortKey="Chao, Nelson J" sort="Chao, Nelson J" uniqKey="Chao N" first="Nelson J." last="Chao">Nelson J. Chao</name>
<affiliation wicri:level="2">
<nlm:aff id="A31">Division of Cell Therapy and Hematologica, Department of Medicine, Duke University Medical Center, Durham, NC</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Caroline du Nord</region>
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<wicri:cityArea>Division of Cell Therapy and Hematologica, Department of Medicine, Duke University Medical Center, Durham</wicri:cityArea>
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<author>
<name sortKey="Aljurf, Mahmoud D" sort="Aljurf, Mahmoud D" uniqKey="Aljurf M" first="Mahmoud D." last="Aljurf">Mahmoud D. Aljurf</name>
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<nlm:aff id="A32">Department of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia</nlm:aff>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Department of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
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</author>
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<name sortKey="Cooper, Brenda W" sort="Cooper, Brenda W" uniqKey="Cooper B" first="Brenda W." last="Cooper">Brenda W. Cooper</name>
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<name sortKey="Hsu, Jack W" sort="Hsu, Jack W" uniqKey="Hsu J" first="Jack W." last="Hsu">Jack W. Hsu</name>
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<nlm:aff id="A35">Division of Hematology & Oncology, Department of Medicine, Shands HealthCare & University of Florida, Gainesville, FL</nlm:aff>
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<region type="state">Floride</region>
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<nlm:aff id="A12">Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison</wicri:cityArea>
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<author>
<name sortKey="Verdonck, Leo F" sort="Verdonck, Leo F" uniqKey="Verdonck L" first="Leo F." last="Verdonck">Leo F. Verdonck</name>
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<wicri:regionArea>Department of Internal Medicine, Isala Clinics, Zwolle</wicri:regionArea>
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<name sortKey="Solh, Melhelm M" sort="Solh, Melhelm M" uniqKey="Solh M" first="Melhelm M." last="Solh">Melhelm M. Solh</name>
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<region type="state">Floride</region>
</placeName>
<wicri:cityArea>Flordia Center for Cellular Therapy, Florida Hospital, Orlando</wicri:cityArea>
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<name sortKey="Norkin, Maxim" sort="Norkin, Maxim" uniqKey="Norkin M" first="Maxim" last="Norkin">Maxim Norkin</name>
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<nlm:aff id="A35">Division of Hematology & Oncology, Department of Medicine, Shands HealthCare & University of Florida, Gainesville, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
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<author>
<name sortKey="Reddy, Vijay" sort="Reddy, Vijay" uniqKey="Reddy V" first="Vijay" last="Reddy">Vijay Reddy</name>
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<nlm:aff id="A38">University of Florida, Gainesville, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>University of Florida, Gainesville</wicri:cityArea>
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<author>
<name sortKey="Martino, Rodrigo" sort="Martino, Rodrigo" uniqKey="Martino R" first="Rodrigo" last="Martino">Rodrigo Martino</name>
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<nlm:aff id="A39">Department of Hematology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Hematology, Hospital de la Santa Creu I Sant Pau, Barcelona</wicri:regionArea>
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<settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
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<nlm:aff id="A40">Division of Cancer Epidemiology & Genetics, NIH-NCI Clinical Genetics Branch, Rockville, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Maryland</region>
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<wicri:cityArea>Division of Cancer Epidemiology & Genetics, NIH-NCI Clinical Genetics Branch, Rockville</wicri:cityArea>
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<author>
<name sortKey="Goldberg, Jenna D" sort="Goldberg, Jenna D" uniqKey="Goldberg J" first="Jenna D." last="Goldberg">Jenna D. Goldberg</name>
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<nlm:aff id="A41">Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York</wicri:cityArea>
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</author>
<author>
<name sortKey="Mccarthy, Philip L" sort="Mccarthy, Philip L" uniqKey="Mccarthy P" first="Philip L." last="Mccarthy">Philip L. Mccarthy</name>
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<nlm:aff id="A42">Blood & Marrow Transplant Program, Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Blood & Marrow Transplant Program, Department of Medicine, Roswell Park Cancer Institute, Buffalo</wicri:cityArea>
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<name sortKey="Perez Sim N, Jose A" sort="Perez Sim N, Jose A" uniqKey="Perez Sim N J" first="José A." last="Pérez-Sim N">José A. Pérez-Sim N</name>
<affiliation wicri:level="1">
<nlm:aff id="A43">Department of Hematology, Instituto de Biomedicina de Sevilla, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Hematology, Instituto de Biomedicina de Sevilla, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
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</author>
<author>
<name sortKey="Khera, Nandita" sort="Khera, Nandita" uniqKey="Khera N" first="Nandita" last="Khera">Nandita Khera</name>
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<nlm:aff id="A44">Department of Hematology/Oncology, Mayo Clinic, Phoenix, AZ</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Arizona</region>
</placeName>
<wicri:cityArea>Department of Hematology/Oncology, Mayo Clinic, Phoenix</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Lewis, Ian D" sort="Lewis, Ian D" uniqKey="Lewis I" first="Ian D." last="Lewis">Ian D. Lewis</name>
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<nlm:aff id="A45">Haematology and Bone Marrow Transplant Unit, Royal Adelaide Hospital, Adelaide, SA, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Haematology and Bone Marrow Transplant Unit, Royal Adelaide Hospital, Adelaide, SA</wicri:regionArea>
<wicri:noRegion>SA</wicri:noRegion>
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</author>
<author>
<name sortKey="Atsuta, Yoshiko" sort="Atsuta, Yoshiko" uniqKey="Atsuta Y" first="Yoshiko" last="Atsuta">Yoshiko Atsuta</name>
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<nlm:aff id="A46">Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya</wicri:regionArea>
<wicri:noRegion>Nagoya</wicri:noRegion>
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<affiliation wicri:level="1">
<nlm:aff id="A47">Nagoya University Graduate School of Medicine, Nagoya, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Nagoya University Graduate School of Medicine, Nagoya</wicri:regionArea>
<wicri:noRegion>Nagoya</wicri:noRegion>
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</author>
<author>
<name sortKey="Olsson, Richard F" sort="Olsson, Richard F" uniqKey="Olsson R" first="Richard F." last="Olsson">Richard F. Olsson</name>
<affiliation wicri:level="3">
<nlm:aff id="A48">Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
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</placeName>
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<country xml:lang="fr">Suède</country>
<wicri:regionArea>Centre for Clinical Research Sörmland, Uppsala University, Uppsala</wicri:regionArea>
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<author>
<name sortKey="Saber, Wael" sort="Saber, Wael" uniqKey="Saber W" first="Wael" last="Saber">Wael Saber</name>
<affiliation wicri:level="2">
<nlm:aff id="A3">Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
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</author>
<author>
<name sortKey="Waller, Edmund K" sort="Waller, Edmund K" uniqKey="Waller E" first="Edmund K." last="Waller">Edmund K. Waller</name>
<affiliation wicri:level="2">
<nlm:aff id="A50">Winship Cancer Institute, Emory University, Atlanta, GA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Géorgie (États-Unis)</region>
</placeName>
<wicri:cityArea>Winship Cancer Institute, Emory University, Atlanta</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Blaise, Didier" sort="Blaise, Didier" uniqKey="Blaise D" first="Didier" last="Blaise">Didier Blaise</name>
<affiliation wicri:level="3">
<nlm:aff id="A51">Deparment of Hematology, Institut Paoli Calmettes, Marseille, France</nlm:aff>
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<wicri:regionArea>Deparment of Hematology, Institut Paoli Calmettes, Marseille</wicri:regionArea>
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<region type="region">Provence-Alpes-Côte d'Azur</region>
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<name sortKey="Pidala, Joseph A" sort="Pidala, Joseph A" uniqKey="Pidala J" first="Joseph A." last="Pidala">Joseph A. Pidala</name>
<affiliation wicri:level="2">
<nlm:aff id="A52">H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>H. Lee Moffitt Cancer Center and Research Institute, Tampa</wicri:cityArea>
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</author>
<author>
<name sortKey="Martin, Paul J" sort="Martin, Paul J" uniqKey="Martin P" first="Paul J." last="Martin">Paul J. Martin</name>
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<nlm:aff id="A13">Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA</nlm:aff>
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<region type="state">Washington (État)</region>
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</author>
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<name sortKey="Satwani, Prakash" sort="Satwani, Prakash" uniqKey="Satwani P" first="Prakash" last="Satwani">Prakash Satwani</name>
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<nlm:aff id="A53">Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Columbia University Medical Center, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
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<author>
<name sortKey="Bornh User, Martin" sort="Bornh User, Martin" uniqKey="Bornh User M" first="Martin" last="Bornh User">Martin Bornh User</name>
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<nlm:aff id="A54">Department of Internal Medicine, University Hospital Dresden, Dresden, Germany</nlm:aff>
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<region type="land" nuts="1">Saxe (Land)</region>
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</affiliation>
</author>
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<name sortKey="Inamoto, Yoshihiro" sort="Inamoto, Yoshihiro" uniqKey="Inamoto Y" first="Yoshihiro" last="Inamoto">Yoshihiro Inamoto</name>
<affiliation wicri:level="2">
<nlm:aff id="A13">Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA</nlm:aff>
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<region type="state">Washington (État)</region>
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<region type="state">Minnesota</region>
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<name sortKey="Horowitz, Mary M" sort="Horowitz, Mary M" uniqKey="Horowitz M" first="Mary M." last="Horowitz">Mary M. Horowitz</name>
<affiliation wicri:level="2">
<nlm:aff id="A3">Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
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<wicri:cityArea>Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
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</author>
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<nlm:aff id="A55">NIH-NCI Experimental Transplantation and Immunology Branch, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Maryland</region>
</placeName>
<wicri:cityArea>NIH-NCI Experimental Transplantation and Immunology Branch, Bethesda</wicri:cityArea>
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<title xml:lang="en" level="a" type="main">Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation – A Report from CIBMTR</title>
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<name sortKey="Arai, Sally" sort="Arai, Sally" uniqKey="Arai S" first="Sally" last="Arai">Sally Arai</name>
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<region type="state">Minnesota</region>
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<country xml:lang="fr">États-Unis</country>
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<region type="state">Wisconsin</region>
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<region type="state">Minnesota</region>
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<nlm:aff id="A3">Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<region type="state">Wisconsin</region>
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<country xml:lang="fr">États-Unis</country>
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<region type="state">Michigan</region>
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</author>
<author>
<name sortKey="Cutler, Corey S" sort="Cutler, Corey S" uniqKey="Cutler C" first="Corey S." last="Cutler">Corey S. Cutler</name>
<affiliation wicri:level="2">
<nlm:aff id="A8">Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Bacigalupo, Andrea A" sort="Bacigalupo, Andrea A" uniqKey="Bacigalupo A" first="Andrea A." last="Bacigalupo">Andrea A. Bacigalupo</name>
<affiliation wicri:level="1">
<nlm:aff id="A9">Department of Hematology, IRCCS AOU San Martino-IST, Genoa, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Hematology, IRCCS AOU San Martino-IST, Genoa</wicri:regionArea>
<wicri:noRegion>Genoa</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Battiwalla, Minoo" sort="Battiwalla, Minoo" uniqKey="Battiwalla M" first="Minoo" last="Battiwalla">Minoo Battiwalla</name>
<affiliation wicri:level="2">
<nlm:aff id="A10">Branch of Hematology, National Heart Lung and Blood Institute, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Branch of Hematology, National Heart Lung and Blood Institute, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Flowers, Mary E" sort="Flowers, Mary E" uniqKey="Flowers M" first="Mary E." last="Flowers">Mary E. Flowers</name>
<affiliation wicri:level="2">
<nlm:aff id="A11">Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Fred Hutchinson Cancer Research Center and University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Juckett, Mark B" sort="Juckett, Mark B" uniqKey="Juckett M" first="Mark B." last="Juckett">Mark B. Juckett</name>
<affiliation wicri:level="2">
<nlm:aff id="A12">Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Lee, Stephanie J" sort="Lee, Stephanie J" uniqKey="Lee S" first="Stephanie J." last="Lee">Stephanie J. Lee</name>
<affiliation wicri:level="2">
<nlm:aff id="A13">Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Loren, Alison W" sort="Loren, Alison W" uniqKey="Loren A" first="Alison W." last="Loren">Alison W. Loren</name>
<affiliation wicri:level="2">
<nlm:aff id="A14">Division of Hematology/Oncology, Abramson Cancer Center, University of Pennsylvania Medical Center, Philadelphia, PA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Division of Hematology/Oncology, Abramson Cancer Center, University of Pennsylvania Medical Center, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Klumpp, Thomas R" sort="Klumpp, Thomas R" uniqKey="Klumpp T" first="Thomas R." last="Klumpp">Thomas R. Klumpp</name>
<affiliation wicri:level="2">
<nlm:aff id="A15">Divison of Bone Marrow Transplantation, Temple Bone Marrow Transplant Program, Philadelphia, PA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Divison of Bone Marrow Transplantation, Temple Bone Marrow Transplant Program, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Prockup, Susan E" sort="Prockup, Susan E" uniqKey="Prockup S" first="Susan E." last="Prockup">Susan E. Prockup</name>
<affiliation wicri:level="2">
<nlm:aff id="A16">Divison of Bone Marrow Transplant, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Divison of Bone Marrow Transplant, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ringden, Olle T H" sort="Ringden, Olle T H" uniqKey="Ringden O" first="Olle T. H." last="Ringdén">Olle T. H. Ringdén</name>
<affiliation wicri:level="3">
<nlm:aff id="A17">Division of Clinical Immunology and Center for Allogeneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Clinical Immunology and Center for Allogeneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm</wicri:regionArea>
<placeName>
<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Savani, Bipin N" sort="Savani, Bipin N" uniqKey="Savani B" first="Bipin N." last="Savani">Bipin N. Savani</name>
<affiliation wicri:level="2">
<nlm:aff id="A18">Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Socie, Gerard" sort="Socie, Gerard" uniqKey="Socie G" first="Gérard" last="Socié">Gérard Socié</name>
<affiliation wicri:level="3">
<nlm:aff id="A19">Division of Hematology, Hopital Saint Louis, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Division of Hematology, Hopital Saint Louis, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Schultz, Kirk R" sort="Schultz, Kirk R" uniqKey="Schultz K" first="Kirk R." last="Schultz">Kirk R. Schultz</name>
<affiliation wicri:level="1">
<nlm:aff id="A20">Department of Pediatric Hematology/Oncology/BMT, British Columbia’s Children’s Hospital, University of British Columbia, Vancouver, British Columbia, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Pediatric Hematology/Oncology/BMT, British Columbia’s Children’s Hospital, University of British Columbia, Vancouver, British Columbia</wicri:regionArea>
<wicri:noRegion>British Columbia</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Spitzer, Thomas" sort="Spitzer, Thomas" uniqKey="Spitzer T" first="Thomas" last="Spitzer">Thomas Spitzer</name>
<affiliation wicri:level="2">
<nlm:aff id="A21">Department of Bone Marrow Transplant-Oncology, Massachusetts General Hospital, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Bone Marrow Transplant-Oncology, Massachusetts General Hospital, Boston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Teshima, Takanori" sort="Teshima, Takanori" uniqKey="Teshima T" first="Takanori" last="Teshima">Takanori Teshima</name>
<affiliation wicri:level="1">
<nlm:aff id="A22">Kyushu University Hospital, Fukuoka, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Kyushu University Hospital, Fukuoka</wicri:regionArea>
<wicri:noRegion>Fukuoka</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Bredeson, Christopher N" sort="Bredeson, Christopher N" uniqKey="Bredeson C" first="Christopher N." last="Bredeson">Christopher N. Bredeson</name>
<affiliation wicri:level="1">
<nlm:aff id="A23">Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medicine, The Ottawa Hospital, Ottawa, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Jacobsohn, David A" sort="Jacobsohn, David A" uniqKey="Jacobsohn D" first="David A." last="Jacobsohn">David A. Jacobsohn</name>
<affiliation wicri:level="2">
<nlm:aff id="A24">Division of Blood and Marrow Transplantation Center for Cancer and Blood Disorders, Children’s National Health Systems, Washington, DC</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">District de Columbia</region>
</placeName>
<wicri:cityArea>Division of Blood and Marrow Transplantation Center for Cancer and Blood Disorders, Children’s National Health Systems, Washington</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hayashi, Robert J" sort="Hayashi, Robert J" uniqKey="Hayashi R" first="Robert J." last="Hayashi">Robert J. Hayashi</name>
<affiliation wicri:level="2">
<nlm:aff id="A25">Division of Pediatric Hematology/Oncology, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Missouri (État)</region>
</placeName>
<wicri:cityArea>Division of Pediatric Hematology/Oncology, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Drobyski, William R" sort="Drobyski, William R" uniqKey="Drobyski W" first="William R." last="Drobyski">William R. Drobyski</name>
<affiliation wicri:level="2">
<nlm:aff id="A26">Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Frangoul, Haydar A" sort="Frangoul, Haydar A" uniqKey="Frangoul H" first="Haydar A." last="Frangoul">Haydar A. Frangoul</name>
<affiliation wicri:level="2">
<nlm:aff id="A27">Division of Hematology-Oncology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Division of Hematology-Oncology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Akpek, Gorgun" sort="Akpek, Gorgun" uniqKey="Akpek G" first="Görgün" last="Akpek">Görgün Akpek</name>
<affiliation wicri:level="2">
<nlm:aff id="A28">Section of Hematology Oncology, Banner MD Anderson Cancer Center, Gilbert, AZ</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Arizona</region>
</placeName>
<wicri:cityArea>Section of Hematology Oncology, Banner MD Anderson Cancer Center, Gilbert</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ho, Vincent T" sort="Ho, Vincent T" uniqKey="Ho V" first="Vincent T." last="Ho">Vincent T. Ho</name>
<affiliation wicri:level="2">
<nlm:aff id="A8">Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Lewis, Victor A" sort="Lewis, Victor A" uniqKey="Lewis V" first="Victor A." last="Lewis">Victor A. Lewis</name>
<affiliation wicri:level="1">
<nlm:aff id="A29">Departments of Oncology, Paediatrics, Alberta Children’s Hospital, Calgary, AB, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Departments of Oncology, Paediatrics, Alberta Children’s Hospital, Calgary, AB</wicri:regionArea>
<wicri:noRegion>AB</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Gale, Robert Peter" sort="Gale, Robert Peter" uniqKey="Gale R" first="Robert Peter" last="Gale">Robert Peter Gale</name>
</author>
<author>
<name sortKey="Koreth, John" sort="Koreth, John" uniqKey="Koreth J" first="John" last="Koreth">John Koreth</name>
<affiliation wicri:level="2">
<nlm:aff id="A8">Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Chao, Nelson J" sort="Chao, Nelson J" uniqKey="Chao N" first="Nelson J." last="Chao">Nelson J. Chao</name>
<affiliation wicri:level="2">
<nlm:aff id="A31">Division of Cell Therapy and Hematologica, Department of Medicine, Duke University Medical Center, Durham, NC</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>Division of Cell Therapy and Hematologica, Department of Medicine, Duke University Medical Center, Durham</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Aljurf, Mahmoud D" sort="Aljurf, Mahmoud D" uniqKey="Aljurf M" first="Mahmoud D." last="Aljurf">Mahmoud D. Aljurf</name>
<affiliation wicri:level="1">
<nlm:aff id="A32">Department of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia</nlm:aff>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Department of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Cooper, Brenda W" sort="Cooper, Brenda W" uniqKey="Cooper B" first="Brenda W." last="Cooper">Brenda W. Cooper</name>
<affiliation wicri:level="2">
<nlm:aff id="A33">Department of Medicine-Hematology and Oncology, University Hospitals Case Medical Center, Cleveland, OH</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Ohio</region>
</placeName>
<wicri:cityArea>Department of Medicine-Hematology and Oncology, University Hospitals Case Medical Center, Cleveland</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Laughlin, Mary J" sort="Laughlin, Mary J" uniqKey="Laughlin M" first="Mary J." last="Laughlin">Mary J. Laughlin</name>
<affiliation wicri:level="2">
<nlm:aff id="A34">Medical Director, Cleveland Cord Blood Center, Cleveland, OH</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Ohio</region>
</placeName>
<wicri:cityArea>Medical Director, Cleveland Cord Blood Center, Cleveland</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hsu, Jack W" sort="Hsu, Jack W" uniqKey="Hsu J" first="Jack W." last="Hsu">Jack W. Hsu</name>
<affiliation wicri:level="2">
<nlm:aff id="A35">Division of Hematology & Oncology, Department of Medicine, Shands HealthCare & University of Florida, Gainesville, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>Division of Hematology & Oncology, Department of Medicine, Shands HealthCare & University of Florida, Gainesville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hematti, Peiman" sort="Hematti, Peiman" uniqKey="Hematti P" first="Peiman" last="Hematti">Peiman Hematti</name>
<affiliation wicri:level="2">
<nlm:aff id="A12">Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Verdonck, Leo F" sort="Verdonck, Leo F" uniqKey="Verdonck L" first="Leo F." last="Verdonck">Leo F. Verdonck</name>
<affiliation wicri:level="1">
<nlm:aff id="A36">Department of Internal Medicine, Isala Clinics, Zwolle, Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, Isala Clinics, Zwolle</wicri:regionArea>
<wicri:noRegion>Zwolle</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Solh, Melhelm M" sort="Solh, Melhelm M" uniqKey="Solh M" first="Melhelm M." last="Solh">Melhelm M. Solh</name>
<affiliation wicri:level="2">
<nlm:aff id="A37">Flordia Center for Cellular Therapy, Florida Hospital, Orlando, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>Flordia Center for Cellular Therapy, Florida Hospital, Orlando</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Norkin, Maxim" sort="Norkin, Maxim" uniqKey="Norkin M" first="Maxim" last="Norkin">Maxim Norkin</name>
<affiliation wicri:level="2">
<nlm:aff id="A35">Division of Hematology & Oncology, Department of Medicine, Shands HealthCare & University of Florida, Gainesville, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>Division of Hematology & Oncology, Department of Medicine, Shands HealthCare & University of Florida, Gainesville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Reddy, Vijay" sort="Reddy, Vijay" uniqKey="Reddy V" first="Vijay" last="Reddy">Vijay Reddy</name>
<affiliation wicri:level="2">
<nlm:aff id="A38">University of Florida, Gainesville, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>University of Florida, Gainesville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Martino, Rodrigo" sort="Martino, Rodrigo" uniqKey="Martino R" first="Rodrigo" last="Martino">Rodrigo Martino</name>
<affiliation wicri:level="3">
<nlm:aff id="A39">Department of Hematology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Hematology, Hospital de la Santa Creu I Sant Pau, Barcelona</wicri:regionArea>
<placeName>
<settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Gadalla, Shahinaz" sort="Gadalla, Shahinaz" uniqKey="Gadalla S" first="Shahinaz" last="Gadalla">Shahinaz Gadalla</name>
<affiliation wicri:level="2">
<nlm:aff id="A40">Division of Cancer Epidemiology & Genetics, NIH-NCI Clinical Genetics Branch, Rockville, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Division of Cancer Epidemiology & Genetics, NIH-NCI Clinical Genetics Branch, Rockville</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Goldberg, Jenna D" sort="Goldberg, Jenna D" uniqKey="Goldberg J" first="Jenna D." last="Goldberg">Jenna D. Goldberg</name>
<affiliation wicri:level="2">
<nlm:aff id="A41">Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Mccarthy, Philip L" sort="Mccarthy, Philip L" uniqKey="Mccarthy P" first="Philip L." last="Mccarthy">Philip L. Mccarthy</name>
<affiliation wicri:level="2">
<nlm:aff id="A42">Blood & Marrow Transplant Program, Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Blood & Marrow Transplant Program, Department of Medicine, Roswell Park Cancer Institute, Buffalo</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Perez Sim N, Jose A" sort="Perez Sim N, Jose A" uniqKey="Perez Sim N J" first="José A." last="Pérez-Sim N">José A. Pérez-Sim N</name>
<affiliation wicri:level="1">
<nlm:aff id="A43">Department of Hematology, Instituto de Biomedicina de Sevilla, Seville, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Hematology, Instituto de Biomedicina de Sevilla, Seville</wicri:regionArea>
<wicri:noRegion>Seville</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Khera, Nandita" sort="Khera, Nandita" uniqKey="Khera N" first="Nandita" last="Khera">Nandita Khera</name>
<affiliation wicri:level="2">
<nlm:aff id="A44">Department of Hematology/Oncology, Mayo Clinic, Phoenix, AZ</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Arizona</region>
</placeName>
<wicri:cityArea>Department of Hematology/Oncology, Mayo Clinic, Phoenix</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Lewis, Ian D" sort="Lewis, Ian D" uniqKey="Lewis I" first="Ian D." last="Lewis">Ian D. Lewis</name>
<affiliation wicri:level="1">
<nlm:aff id="A45">Haematology and Bone Marrow Transplant Unit, Royal Adelaide Hospital, Adelaide, SA, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Haematology and Bone Marrow Transplant Unit, Royal Adelaide Hospital, Adelaide, SA</wicri:regionArea>
<wicri:noRegion>SA</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Atsuta, Yoshiko" sort="Atsuta, Yoshiko" uniqKey="Atsuta Y" first="Yoshiko" last="Atsuta">Yoshiko Atsuta</name>
<affiliation wicri:level="1">
<nlm:aff id="A46">Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya</wicri:regionArea>
<wicri:noRegion>Nagoya</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="A47">Nagoya University Graduate School of Medicine, Nagoya, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Nagoya University Graduate School of Medicine, Nagoya</wicri:regionArea>
<wicri:noRegion>Nagoya</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Olsson, Richard F" sort="Olsson, Richard F" uniqKey="Olsson R" first="Richard F." last="Olsson">Richard F. Olsson</name>
<affiliation wicri:level="3">
<nlm:aff id="A48">Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
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<settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
<affiliation wicri:level="4">
<nlm:aff id="A49">Centre for Clinical Research Sörmland, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Centre for Clinical Research Sörmland, Uppsala University, Uppsala</wicri:regionArea>
<orgName type="university">Université d'Uppsala</orgName>
<placeName>
<settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Saber, Wael" sort="Saber, Wael" uniqKey="Saber W" first="Wael" last="Saber">Wael Saber</name>
<affiliation wicri:level="2">
<nlm:aff id="A3">Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Waller, Edmund K" sort="Waller, Edmund K" uniqKey="Waller E" first="Edmund K." last="Waller">Edmund K. Waller</name>
<affiliation wicri:level="2">
<nlm:aff id="A50">Winship Cancer Institute, Emory University, Atlanta, GA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Géorgie (États-Unis)</region>
</placeName>
<wicri:cityArea>Winship Cancer Institute, Emory University, Atlanta</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Blaise, Didier" sort="Blaise, Didier" uniqKey="Blaise D" first="Didier" last="Blaise">Didier Blaise</name>
<affiliation wicri:level="3">
<nlm:aff id="A51">Deparment of Hematology, Institut Paoli Calmettes, Marseille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Deparment of Hematology, Institut Paoli Calmettes, Marseille</wicri:regionArea>
<placeName>
<region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Pidala, Joseph A" sort="Pidala, Joseph A" uniqKey="Pidala J" first="Joseph A." last="Pidala">Joseph A. Pidala</name>
<affiliation wicri:level="2">
<nlm:aff id="A52">H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Floride</region>
</placeName>
<wicri:cityArea>H. Lee Moffitt Cancer Center and Research Institute, Tampa</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Martin, Paul J" sort="Martin, Paul J" uniqKey="Martin P" first="Paul J." last="Martin">Paul J. Martin</name>
<affiliation wicri:level="2">
<nlm:aff id="A13">Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Satwani, Prakash" sort="Satwani, Prakash" uniqKey="Satwani P" first="Prakash" last="Satwani">Prakash Satwani</name>
<affiliation wicri:level="2">
<nlm:aff id="A53">Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Columbia University Medical Center, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Columbia University Medical Center, New York</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Bornh User, Martin" sort="Bornh User, Martin" uniqKey="Bornh User M" first="Martin" last="Bornh User">Martin Bornh User</name>
<affiliation wicri:level="3">
<nlm:aff id="A54">Department of Internal Medicine, University Hospital Dresden, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Internal Medicine, University Hospital Dresden, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Inamoto, Yoshihiro" sort="Inamoto, Yoshihiro" uniqKey="Inamoto Y" first="Yoshihiro" last="Inamoto">Yoshihiro Inamoto</name>
<affiliation wicri:level="2">
<nlm:aff id="A13">Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Divison of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Weisdorf, Daniel J" sort="Weisdorf, Daniel J" uniqKey="Weisdorf D" first="Daniel J." last="Weisdorf">Daniel J. Weisdorf</name>
<affiliation wicri:level="2">
<nlm:aff id="A2">Division of Hematology, Oncology and Transplant, University of Minnesota Medical Center, Minneapolis, MN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>Division of Hematology, Oncology and Transplant, University of Minnesota Medical Center, Minneapolis</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Horowitz, Mary M" sort="Horowitz, Mary M" uniqKey="Horowitz M" first="Mary M." last="Horowitz">Mary M. Horowitz</name>
<affiliation wicri:level="2">
<nlm:aff id="A3">Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Pavletic, Steven Z" sort="Pavletic, Steven Z" uniqKey="Pavletic S" first="Steven Z." last="Pavletic">Steven Z. Pavletic</name>
<affiliation wicri:level="2">
<nlm:aff id="A55">NIH-NCI Experimental Transplantation and Immunology Branch, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Maryland</region>
</placeName>
<wicri:cityArea>NIH-NCI Experimental Transplantation and Immunology Branch, Bethesda</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation</title>
<idno type="ISSN">1083-8791</idno>
<idno type="eISSN">1523-6536</idno>
<imprint>
<date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adolescent</term>
<term>Adult</term>
<term>Bone Marrow Transplantation (adverse effects)</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Chronic Disease</term>
<term>Female</term>
<term>Graft vs Host Disease (etiology)</term>
<term>Graft vs Host Disease (mortality)</term>
<term>Graft vs Host Disease (pathology)</term>
<term>Hematopoietic Stem Cell Transplantation (adverse effects)</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>International Cooperation</term>
<term>Leukemia, Myelogenous, Chronic, BCR-ABL Positive (mortality)</term>
<term>Leukemia, Myelogenous, Chronic, BCR-ABL Positive (pathology)</term>
<term>Leukemia, Myelogenous, Chronic, BCR-ABL Positive (therapy)</term>
<term>Leukemia, Myeloid, Acute (mortality)</term>
<term>Leukemia, Myeloid, Acute (pathology)</term>
<term>Leukemia, Myeloid, Acute (therapy)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myeloablative Agonists (therapeutic use)</term>
<term>Myelodysplastic Syndromes (mortality)</term>
<term>Myelodysplastic Syndromes (pathology)</term>
<term>Myelodysplastic Syndromes (therapy)</term>
<term>Odds Ratio</term>
<term>Survival Analysis</term>
<term>Transplantation, Homologous</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Agonistes myélo-ablatifs (usage thérapeutique)</term>
<term>Analyse de survie</term>
<term>Coopération internationale</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Leucémie aigüe myéloïde ()</term>
<term>Leucémie aigüe myéloïde (anatomopathologie)</term>
<term>Leucémie aigüe myéloïde (mortalité)</term>
<term>Leucémie myéloïde chronique BCR-ABL positive ()</term>
<term>Leucémie myéloïde chronique BCR-ABL positive (anatomopathologie)</term>
<term>Leucémie myéloïde chronique BCR-ABL positive (mortalité)</term>
<term>Maladie chronique</term>
<term>Maladie du greffon contre l'hôte (anatomopathologie)</term>
<term>Maladie du greffon contre l'hôte (mortalité)</term>
<term>Maladie du greffon contre l'hôte (étiologie)</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Odds ratio</term>
<term>Syndromes myélodysplasiques ()</term>
<term>Syndromes myélodysplasiques (anatomopathologie)</term>
<term>Syndromes myélodysplasiques (mortalité)</term>
<term>Transplantation de cellules souches hématopoïétiques (effets indésirables)</term>
<term>Transplantation de moelle osseuse (effets indésirables)</term>
<term>Transplantation homologue</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Myeloablative Agonists</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Bone Marrow Transplantation</term>
<term>Hematopoietic Stem Cell Transplantation</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Leucémie aigüe myéloïde</term>
<term>Leucémie myéloïde chronique BCR-ABL positive</term>
<term>Maladie du greffon contre l'hôte</term>
<term>Syndromes myélodysplasiques</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr">
<term>Transplantation de cellules souches hématopoïétiques</term>
<term>Transplantation de moelle osseuse</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Graft vs Host Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en">
<term>Graft vs Host Disease</term>
<term>Leukemia, Myelogenous, Chronic, BCR-ABL Positive</term>
<term>Leukemia, Myeloid, Acute</term>
<term>Myelodysplastic Syndromes</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr">
<term>Leucémie aigüe myéloïde</term>
<term>Leucémie myéloïde chronique BCR-ABL positive</term>
<term>Maladie du greffon contre l'hôte</term>
<term>Syndromes myélodysplasiques</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Graft vs Host Disease</term>
<term>Leukemia, Myelogenous, Chronic, BCR-ABL Positive</term>
<term>Leukemia, Myeloid, Acute</term>
<term>Myelodysplastic Syndromes</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Leukemia, Myelogenous, Chronic, BCR-ABL Positive</term>
<term>Leukemia, Myeloid, Acute</term>
<term>Myelodysplastic Syndromes</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr">
<term>Agonistes myélo-ablatifs</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr">
<term>Maladie du greffon contre l'hôte</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adolescent</term>
<term>Adult</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Chronic Disease</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>International Cooperation</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Odds Ratio</term>
<term>Survival Analysis</term>
<term>Transplantation, Homologous</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analyse de survie</term>
<term>Coopération internationale</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Leucémie aigüe myéloïde</term>
<term>Leucémie myéloïde chronique BCR-ABL positive</term>
<term>Maladie chronique</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Odds ratio</term>
<term>Syndromes myélodysplasiques</term>
<term>Transplantation homologue</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p id="P3">Although transplant practices have changed over the last decades there is no information on trends in incidence and outcome of cGVHD over time. This study utilized the central database of the Center for International Blood and Marrow Transplant Research (CIBMTR) to describe the time trends for cGVHD incidence, non-relapse mortality, and the risk factors for cGVHD. The 12-year period was divided into three intervals: 1995-1999, 2000-2003, 2004-2007, and included 26,563 patients with acute leukemia, chronic myeloid leukemia and myelodysplastic syndrome. In the multivariate analysis, the incidence of cGVHD was shown to be increased in more recent years (odds ratio= 1.19, p<0.0001) and this trend was still seen when adjusting for donor type, graft type, or conditioning intensity. In patients with cGVHD, non-relapse mortality has decreased over time, but at 5-years there were no significant differences among different time periods. Risk factors for cGVHD were in line with previous studies. This is the first comprehensive characterization of the trends in cGVHD incidence and underscores the mounting need for addressing this major late complication of transplantation in future research.</p>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Allemagne</li>
<li>Arabie saoudite</li>
<li>Australie</li>
<li>Canada</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Japon</li>
<li>Pays-Bas</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region>
<li>Arizona</li>
<li>Californie</li>
<li>Caroline du Nord</li>
<li>Catalogne</li>
<li>District de Columbia</li>
<li>District de Dresde</li>
<li>East Middle Sweden</li>
<li>Floride</li>
<li>Géorgie (États-Unis)</li>
<li>Maryland</li>
<li>Massachusetts</li>
<li>Michigan</li>
<li>Minnesota</li>
<li>Missouri (État)</li>
<li>Ohio</li>
<li>Pennsylvanie</li>
<li>Provence-Alpes-Côte d'Azur</li>
<li>Saxe (Land)</li>
<li>Svealand</li>
<li>Tennessee</li>
<li>Washington (État)</li>
<li>Wisconsin</li>
<li>État de New York</li>
<li>Île-de-France</li>
</region>
<settlement>
<li>Barcelone</li>
<li>Dresde</li>
<li>Marseille</li>
<li>Paris</li>
<li>Stockholm</li>
<li>Uppsala</li>
</settlement>
<orgName>
<li>Université d'Uppsala</li>
</orgName>
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<tree>
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<name sortKey="Gale, Robert Peter" sort="Gale, Robert Peter" uniqKey="Gale R" first="Robert Peter" last="Gale">Robert Peter Gale</name>
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<region name="Californie">
<name sortKey="Arai, Sally" sort="Arai, Sally" uniqKey="Arai S" first="Sally" last="Arai">Sally Arai</name>
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<name sortKey="Arora, Mukta" sort="Arora, Mukta" uniqKey="Arora M" first="Mukta" last="Arora">Mukta Arora</name>
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<name sortKey="Cooper, Brenda W" sort="Cooper, Brenda W" uniqKey="Cooper B" first="Brenda W." last="Cooper">Brenda W. Cooper</name>
<name sortKey="Couriel, Daniel R" sort="Couriel, Daniel R" uniqKey="Couriel D" first="Daniel R." last="Couriel">Daniel R. Couriel</name>
<name sortKey="Cutler, Corey S" sort="Cutler, Corey S" uniqKey="Cutler C" first="Corey S." last="Cutler">Corey S. Cutler</name>
<name sortKey="Drobyski, William R" sort="Drobyski, William R" uniqKey="Drobyski W" first="William R." last="Drobyski">William R. Drobyski</name>
<name sortKey="Flowers, Mary E" sort="Flowers, Mary E" uniqKey="Flowers M" first="Mary E." last="Flowers">Mary E. Flowers</name>
<name sortKey="Frangoul, Haydar A" sort="Frangoul, Haydar A" uniqKey="Frangoul H" first="Haydar A." last="Frangoul">Haydar A. Frangoul</name>
<name sortKey="Gadalla, Shahinaz" sort="Gadalla, Shahinaz" uniqKey="Gadalla S" first="Shahinaz" last="Gadalla">Shahinaz Gadalla</name>
<name sortKey="Goldberg, Jenna D" sort="Goldberg, Jenna D" uniqKey="Goldberg J" first="Jenna D." last="Goldberg">Jenna D. Goldberg</name>
<name sortKey="Hayashi, Robert J" sort="Hayashi, Robert J" uniqKey="Hayashi R" first="Robert J." last="Hayashi">Robert J. Hayashi</name>
<name sortKey="He, Wensheng" sort="He, Wensheng" uniqKey="He W" first="Wensheng" last="He">Wensheng He</name>
<name sortKey="Hematti, Peiman" sort="Hematti, Peiman" uniqKey="Hematti P" first="Peiman" last="Hematti">Peiman Hematti</name>
<name sortKey="Ho, Vincent T" sort="Ho, Vincent T" uniqKey="Ho V" first="Vincent T." last="Ho">Vincent T. Ho</name>
<name sortKey="Horowitz, Mary M" sort="Horowitz, Mary M" uniqKey="Horowitz M" first="Mary M." last="Horowitz">Mary M. Horowitz</name>
<name sortKey="Hsu, Jack W" sort="Hsu, Jack W" uniqKey="Hsu J" first="Jack W." last="Hsu">Jack W. Hsu</name>
<name sortKey="Inamoto, Yoshihiro" sort="Inamoto, Yoshihiro" uniqKey="Inamoto Y" first="Yoshihiro" last="Inamoto">Yoshihiro Inamoto</name>
<name sortKey="Jacobsohn, David A" sort="Jacobsohn, David A" uniqKey="Jacobsohn D" first="David A." last="Jacobsohn">David A. Jacobsohn</name>
<name sortKey="Juckett, Mark B" sort="Juckett, Mark B" uniqKey="Juckett M" first="Mark B." last="Juckett">Mark B. Juckett</name>
<name sortKey="Khera, Nandita" sort="Khera, Nandita" uniqKey="Khera N" first="Nandita" last="Khera">Nandita Khera</name>
<name sortKey="Klumpp, Thomas R" sort="Klumpp, Thomas R" uniqKey="Klumpp T" first="Thomas R." last="Klumpp">Thomas R. Klumpp</name>
<name sortKey="Koreth, John" sort="Koreth, John" uniqKey="Koreth J" first="John" last="Koreth">John Koreth</name>
<name sortKey="Laughlin, Mary J" sort="Laughlin, Mary J" uniqKey="Laughlin M" first="Mary J." last="Laughlin">Mary J. Laughlin</name>
<name sortKey="Lee, Stephanie J" sort="Lee, Stephanie J" uniqKey="Lee S" first="Stephanie J." last="Lee">Stephanie J. Lee</name>
<name sortKey="Loren, Alison W" sort="Loren, Alison W" uniqKey="Loren A" first="Alison W." last="Loren">Alison W. Loren</name>
<name sortKey="Martin, Paul J" sort="Martin, Paul J" uniqKey="Martin P" first="Paul J." last="Martin">Paul J. Martin</name>
<name sortKey="Mccarthy, Philip L" sort="Mccarthy, Philip L" uniqKey="Mccarthy P" first="Philip L." last="Mccarthy">Philip L. Mccarthy</name>
<name sortKey="Norkin, Maxim" sort="Norkin, Maxim" uniqKey="Norkin M" first="Maxim" last="Norkin">Maxim Norkin</name>
<name sortKey="Pavletic, Steven Z" sort="Pavletic, Steven Z" uniqKey="Pavletic S" first="Steven Z." last="Pavletic">Steven Z. Pavletic</name>
<name sortKey="Pidala, Joseph A" sort="Pidala, Joseph A" uniqKey="Pidala J" first="Joseph A." last="Pidala">Joseph A. Pidala</name>
<name sortKey="Prockup, Susan E" sort="Prockup, Susan E" uniqKey="Prockup S" first="Susan E." last="Prockup">Susan E. Prockup</name>
<name sortKey="Reddy, Vijay" sort="Reddy, Vijay" uniqKey="Reddy V" first="Vijay" last="Reddy">Vijay Reddy</name>
<name sortKey="Saber, Wael" sort="Saber, Wael" uniqKey="Saber W" first="Wael" last="Saber">Wael Saber</name>
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